Gliklich R E, Eavey R D, Iannuzzi R A, Camacho A E
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, USA.
Arch Otolaryngol Head Neck Surg. 1996 Feb;122(2):135-9. doi: 10.1001/archotol.1996.01890140023006.
Acute mastoiditis persists as a serious infection despite a dramatic decline in incidence coincident with the introduction of antibiotic therapy.
To assist the contemporary practitioner in the recognition and management of acute mastoiditis through the assessment of a large series of patients.
Retrospective case series comprising 124 patients with acute mastoiditis.
Pediatric and adult otology referral center.
Selected clinical parameters. Risk factors for necessity of surgical intervention and for increased length of hospitalization were analyzed by a stepwise logistic regression model.
A history of antecedent acute otitis media was absent in 45% of patients. Pain (98%) was the most common presenting symptom. Physical signs included an abnormal-appearing tympanic membrane (88%), fever (83%), a narrowed external auditory canal (80%), and postauricular edema (76%). Streptococcus pneumoniae was the most commonly isolated organism. Mastoid surgery was required in 62% of the patients. An elevated white blood cell count (relative risk [RR], 7.4; P < .01), proptosis of the auricle (RR, 4.5; P = .03), and fever on admission (RR, 7.3; P = .05) were risk factors for surgical intervention. All 33 patients with complications (27%) proceeded to surgical intervention. The average length of hospital stay was 7.9 days. The strongest predictor for an increased length of hospital stay was whether the patient required surgery (RR, 3.7; P = .002).
Acute mastoiditis remains a potentially serious otologic infection. Not all patients present with a classic history or physical examination. Therapeutic mastoidectomy is often required.
尽管随着抗生素治疗的引入发病率显著下降,但急性乳突炎仍然是一种严重的感染。
通过对大量患者的评估,协助当代从业者识别和管理急性乳突炎。
回顾性病例系列,包括124例急性乳突炎患者。
儿科和成人耳科转诊中心。
选定的临床参数。通过逐步逻辑回归模型分析手术干预必要性和住院时间延长的危险因素。
45%的患者无前驱急性中耳炎病史。疼痛(98%)是最常见的症状。体征包括鼓膜外观异常(88%)、发热(83%)、外耳道狭窄(80%)和耳后水肿(76%)。肺炎链球菌是最常分离出的病原体。62%的患者需要进行乳突手术。白细胞计数升高(相对风险[RR],7.4;P <.01)、耳廓突出(RR,4.5;P =.03)和入院时发热(RR,7.3;P =.05)是手术干预的危险因素。所有33例有并发症的患者(27%)均进行了手术干预。平均住院时间为7.9天。住院时间延长的最强预测因素是患者是否需要手术(RR,3.7;P =.002)。
急性乳突炎仍然是一种潜在的严重耳科感染。并非所有患者都有典型的病史或体格检查表现。通常需要进行治疗性乳突切除术。