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[冬眠期间大脑血清素的氧化脱氨基作用与单胺氧化酶活性及温度变化之间的关系]

[Relationship between oxidative deamination of cerebral seroton in during hibernation and changes in monoamine oxidase activity and temperature].

作者信息

Voĭtenko N N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1977 Mar;63(3):359-64.

PMID:863031
Abstract

The highest MAO was found in alert ground squirrels and it became minimum in hibernating animals. The temperature relations of the oxidative serotonin desamination (OSD) in alert ground squirrels was relatively low from 7 to 37 degrees C. At the beginning of hibernation OSD did not differ from that of alert animals at 22--37 degrees C, while at 7--22 degrees C it was significantly lower--about 1.0. In hibernating ground squirrels, high OSD was observed at low and high temperatures in all parts of the brain except hypothalamus. At awaikening OSD remained high.

摘要

在警觉的地松鼠中发现单胺氧化酶(MAO)活性最高,而在冬眠动物中则降至最低。警觉地松鼠中氧化5-羟色胺脱氨基作用(OSD)的温度关系在7至37摄氏度时相对较低。在冬眠开始时,22至37摄氏度下的OSD与警觉动物的无差异,而在7至22摄氏度时则显著更低——约为1.0。在冬眠的地松鼠中,除下丘脑外,大脑所有部位在低温和高温下均观察到高OSD活性。觉醒时OSD活性仍然很高。

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