Guzenko V N, Danil'chenko S A, Shevchenko N I
Lik Sprava. 1995 May-Jun(5-6):109-12.
A study was made of morphofunctional changes in the kidneys depending on duration of ischemia and use of the drug combination proposed by the contributors to the article, for pharmacological protection of the kidney. The examination of intraoperative renal biopsy specimens revealed the hystological structure of the kidney to be more intact, with its functional capacity tending to restore more readily than in control, in those patients in whom pharmacological protection had been embarked on. Constricting the renal artery and carrying on pharmacological protection of kidney we succeeded in effecting a complete elimination of the coral-like calculus fragments in favourable conditions on a "dry" organ, being able to manage with almost non-traumatic nephrotomy associated with minimum loss of blood, which fact resulted in the reduction of the lithogenesis recurrence rate by 17 %.
针对肾脏的形态功能变化进行了一项研究，该变化取决于缺血持续时间以及本文作者所提出的用于肾脏药理保护的药物组合的使用情况。对术中肾活检标本的检查显示，在接受了药理保护的患者中，肾脏的组织学结构更完整，其功能能力比对照组更易于恢复。通过结扎肾动脉并进行肾脏药理保护，我们成功地在“干燥”器官的有利条件下完全清除了珊瑚状结石碎片，能够采用几乎无创的肾切开术，且失血极少，这一事实使结石复发率降低了17%。
