[Plasmapheresis efficacy in the treatment of patients with chronic cholestatic hepatitis and primary biliary liver cirrhosis].

Effectiveness of plasmapheresis in a combined treatment of 46 patients with chronic cholestatic hepatitis and 30 with primary biliary cirrhosis of the liver was studied. Gratifying therapeutic results from plasmapheresis were achieved in 62 patients (81.5%). Time-related clinical manifestations of the illness, biochemical and immunological indices in the early post-plasmapheresis period were different in the groups studied. The mechanisms of therapeutic effect of plasmapheresis in patients with chronic cholestatic diseases of the liver were found to be chiefly due to its immunocorrective action, elimination of toxic products, returning to normal of rheological parameters of blood.