Cohen T D, Gross M B, Preminger G M
Division of Urology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA.
Urology. 1996 Mar;47(3):317-23. doi: 10.1016/S0090-4295(99)80445-2.
There are few data on the long-term effectiveness of various endoureterotomy procedures. One such technique for the treatment of ureteral strictures and ureteropelvic junction (UPJ) obstruction utilizes a recently developed ureteral cutting balloon catheter, Acucise. This device may be used under fluoroscopic guidance alone, which significantly reduces operating time. The purpose of this study is to determine the long-term efficacy of the Acucise balloon in treatment of ureteral strictures and UPJ obstruction.
Fifteen patients have been treated with the Acucise balloon, with an average follow-up of 21.6 months. Five of the patients have been followed for more than 2 years, and 11 of the patients had greater than 1 year follow-up.
The overall success rate, defined as resolution of obstruction radiographically or disappearance of symptoms, or both, was 73%, with only 4 overt failures. All but one of the procedures were completed in 45 minutes or less, and 13 of the 15 patients were treated as outpatients. There were two significant complications. Seventy-five percent (3 of 4) of the treatment failures occurred within the first 4 months following original procedure. Of the 4 total failures. 2 patients had ureteral strictures greater than 2 cm in length, which were likely ischemic in nature secondary to previous surgeries. One patient, with a primary UPJ obstruction, was found to have a crossing vessel at subsequent open pyeloplasty.
The Acucise cutting balloon offers the urologist a rapid and effective alternative for the management of ureteral strictures and UPJ obstruction. In our experience, early results (3 to 4 months) are usually indicative of long-term success. Proper patient selection may further improve long-term results of this simple, innovative technique.
关于各种腔内输尿管切开术的长期疗效的数据较少。一种用于治疗输尿管狭窄和肾盂输尿管连接处(UPJ)梗阻的技术是使用一种最近研发的输尿管切割球囊导管,即Acucise。该装置可仅在荧光镜引导下使用,这显著缩短了手术时间。本研究的目的是确定Acucise球囊治疗输尿管狭窄和UPJ梗阻的长期疗效。
15例患者接受了Acucise球囊治疗,平均随访21.6个月。其中5例患者随访时间超过2年,11例患者随访时间超过1年。
总体成功率定义为影像学上梗阻解除或症状消失,或两者皆有,为73%,仅有4例明显失败。除1例手术外,所有手术均在45分钟或更短时间内完成,15例患者中有13例作为门诊患者接受治疗。有2例严重并发症。75%(4例中的3例)的治疗失败发生在初次手术后的前4个月内。在4例总体失败病例中,2例患者的输尿管狭窄长度超过2 cm,可能因既往手术继发缺血性狭窄。1例原发性UPJ梗阻患者在随后的开放性肾盂成形术中发现有交叉血管。
Acucise切割球囊为泌尿外科医生治疗输尿管狭窄和UPJ梗阻提供了一种快速有效的替代方法。根据我们的经验,早期结果(3至4个月)通常预示着长期成功。合理选择患者可能会进一步改善这种简单创新技术的长期效果。