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Synthesis and anticonvulsant activity of new acylthiosemicarbazides and thiazolidones.

作者信息

Gürsoy A, Karali N

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.

出版信息

Farmaco. 1995 Dec;50(12):857-66.

PMID:8634077
Abstract

A number of 1-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetyl)-4-substituted thiosemicarbazide and 2-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetylhydrazono)-3-sub stituted 4-thiazolidone derivatives were synthesized and evaluated for anticonvulsant activity. Some of the tested compounds showed significant activity against MES and ScMet induced seizures.

摘要

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