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High-performance liquid chromatographic determination of bisacodyl in pharmaceutical dosage forms marketed in Australia.

作者信息

Bradshaw K M, Burnett J, Sidhu A S

机构信息

Pharmaceutical Chemistry Section, Therapeutic Goods Administration Laboratories, Woden, Australia.

出版信息

J Pharm Biomed Anal. 1995 Oct;13(11):1355-62. doi: 10.1016/0731-7085(95)01547-x.

Abstract

HPLC methods have been developed for the assay of bisacodyl in various pharmaceutical forms. The extraction procedures are simple and the HPLC conditions separate bisacodyl from its degradation products. The chromatography was performed using a Merck LiChrospher RP-select B column, a mobile phase of 55% acetonitrile/45% 0.05 M KH2PO4 and detection by UV at 214 nm.

摘要

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