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蛋白质能量营养不良对循环甲状腺激素的影响。

Effects of protein energy malnutrition on circulating thyroid hormones.

作者信息

Turkay S, Kus S, Gokalp A, Baskin E, Onal A

机构信息

Department of Pediatrics, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.

出版信息

Indian Pediatr. 1995 Feb;32(2):193-7.

PMID:8635781
Abstract

The effect of protein energy malnutrition (PEM) in the children on serum levels of total thyroxine (TT4), total triodothyronine (TT3) and thyrotropin (TSH) were evaluated. There were 107 children aged 2 to 60 months in the malnutrition group and 54 healthy age and sex matched controls. Serum TT4 and TT3 were all reduced in the malnutrition group. This decrease in TT3 was more significant (p < 0.01) in severe malnutrition than in mild PEM. Serum TSH levels in the malnutrition and control groups were similar. These results suggest that the children remained euthyroid and represent an adaptive response to protein energy malnutrition.

摘要

评估蛋白质能量营养不良(PEM)对儿童血清总甲状腺素(TT4)、总三碘甲状腺原氨酸(TT3)和促甲状腺激素(TSH)水平的影响。营养不良组有107名年龄在2至60个月的儿童,另有54名年龄和性别匹配的健康对照。营养不良组的血清TT4和TT3均降低。与轻度蛋白质能量营养不良相比,重度营养不良时TT3的降低更为显著(p < 0.01)。营养不良组和对照组的血清TSH水平相似。这些结果表明,这些儿童甲状腺功能正常,代表了对蛋白质能量营养不良的一种适应性反应。

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