Fox K M, Hawkes W G, Magaziner J, Zimmerman S I, Hebel J R
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, USA.
J Am Geriatr Soc. 1996 Apr;44(4):371-6. doi: 10.1111/j.1532-5415.1996.tb06404.x.
To determine whether there is a group of recent hip fracture patients who exhibit the signs of failure to thrive and to identify potential precursors to their decline in physical functioning.
Prospective (nonintervention) study of hip fracture recovery; patients were assessed in the hospital and at 2, 6, 12, 18, and 24 months post-fracture.
Hip fracture patients admitted to one of eight Baltimore area hospitals from the community with a new fracture of the proximal femur between January 1, 1990, and June 15, 1991.
Patients were 65 years of age and older and lived in the community before the fracture. A total of 804 patients were eligible for the study; the present study analyses were restricted to the 252 patients who survived 1 year and had a self-report assessment at 6 and 12 months post-fracture.
A questionnaire administered during hospitalization assessed pre-fracture functional and health status and current affective and cognitive status. In-home interviews post-fracture ascertained dependence and difficulty with physical and instrumental activities of daily living. Abstraction of the medical records provided information about comorbidities, surgical procedure, and hospital length of stay.
Patients who declined in ability to walk from 6 to 12 months post-fracture had greater use of health resources (more hospitalizations) and poorer physical functioning up to 2 years post-fracture. Impaired function in physical activities of daily living at 6 months, high glucose, calcium, and CO2 at admission, and low BUN and creatinine at admission were more prevalent among decliners than among non-decliners.
Findings indicate that certain older hip fracture patients begin to exhibit signs and symptoms of failure to thrive. About 10% of patients who survived at least 1 year after fracture could not retain their recovery level of functioning after 6 months and began to decline further. High glucose and CO2 and low BUN and creatinine on hospital admission were associated with later functional decline among hip fracture patients, but their clinical significance is uncertain.
确定是否存在一组近期髋部骨折患者表现出衰弱迹象,并识别其身体功能下降的潜在先兆。
髋部骨折恢复的前瞻性(非干预性)研究;在医院以及骨折后2、6、12、18和24个月对患者进行评估。
1990年1月1日至1991年6月15日期间,巴尔的摩地区八家医院之一收治的社区近端股骨新骨折的髋部骨折患者。
患者年龄在65岁及以上,骨折前居住在社区。共有804名患者符合研究条件;本研究分析仅限于252名存活1年且在骨折后6个月和12个月进行了自我报告评估的患者。
住院期间发放的问卷评估骨折前的功能和健康状况以及当前的情感和认知状况。骨折后的家庭访谈确定日常生活中身体和工具性活动的依赖性和困难程度。病历摘要提供了有关合并症、手术程序和住院时间的信息。
骨折后6至12个月步行能力下降的患者在骨折后2年内使用了更多的医疗资源(住院次数更多)且身体功能更差。在功能下降者中,6个月时日常生活身体活动功能受损、入院时高血糖、高钙和高二氧化碳以及入院时低尿素氮和肌酐的情况比非功能下降者更为普遍。
研究结果表明,某些老年髋部骨折患者开始出现衰弱的体征和症状。骨折后至少存活1年的患者中,约10%在6个月后无法维持其恢复的功能水平,并开始进一步下降。入院时高血糖、高二氧化碳以及低尿素氮和肌酐与髋部骨折患者后期的功能下降有关,但其临床意义尚不确定。