Machado M H, Clode N, Graça L M, Cardoso C G
Serviço de Obstetrícia e Ginecologia, Hospital de Santa Maria/ Faculdade de Medicina de Lisboa.
Acta Med Port. 1996 Jan;9(1):7-14.
The epidemiologic aspects of 311 consecutive cases of hypertension associated with pregnancy seen in the Department of Obstetrics and Gynecology, Hospital de Santa Maria/University of Lisbon Medical School between January 1st 1988 and December 31st 1992, are reviewed. Seventeen cases were multifetal pregnancies. Using the criteria proposed by the American College of Obstetricians and Gynecologists the cases were classified as follows: Mild preeclampsia, 64 cases (7 in twins); severe preeclampsia 50 cases (5 in twins); chronic hypertensive disease, 81 (1 in twins); chronic hypertension with superimposed preeclampsia, 16 (all singleton pregnancies); transient hypertension of pregnancy, 84 (4 in twins); unclassified hypertension, 16 cases of singleton pregnancies. No maternal deaths occurred. The most frequent maternal complications (eclampsia, HELLP syndrome, abruptio placentae and acute renal failure) were seen in preeclampsia (mild and severe forms). Only 2 significant maternal complications were observed in the cases of superimposed preeclampsia on chronic hypertensive disease. In the other groups maternal complications were seldom seen. Excepting in transient hypertension, perinatal morbidity and mortality were frequent in all groups, specially in severe preeclampsia and superimposed preeclampsia, when the delivery occurred before 34 weeks; after that time of pregnancy there were no neonatal deaths in any of the groups and intrauterine growth retardation and fetal distress were the most common fetal complications in all groups. In the whole, uncomplicated chronic hypertension and transient hypertension of pregnancy were the clinical situations in which maternal and perinatal complications were milder and less frequent. No perinatal problems were found in the group of unclassified hypertension.
回顾了1988年1月1日至1992年12月31日期间在里斯本大学医学院圣玛丽亚医院妇产科连续诊治的311例妊娠高血压病例的流行病学情况。其中17例为多胎妊娠。按照美国妇产科医师学会提出的标准,这些病例分类如下:轻度子痫前期64例(双胎妊娠7例);重度子痫前期50例(双胎妊娠5例);慢性高血压病81例(双胎妊娠1例);慢性高血压并发子痫前期16例(均为单胎妊娠);妊娠一过性高血压84例(双胎妊娠4例);未分类高血压,单胎妊娠16例。无孕产妇死亡病例。最常见的孕产妇并发症(子痫、HELLP综合征、胎盘早剥和急性肾衰竭)见于子痫前期(轻度和重度)。慢性高血压并发子痫前期病例仅观察到2例严重孕产妇并发症。其他组很少见到孕产妇并发症。除妊娠一过性高血压外,所有组围产期发病率和死亡率均较高,尤其是重度子痫前期和慢性高血压并发子痫前期,若在孕34周前分娩;孕34周后,所有组均无新生儿死亡,宫内生长受限和胎儿窘迫是所有组最常见的胎儿并发症。总体而言,未合并症的慢性高血压和妊娠一过性高血压是孕产妇和围产期并发症较轻且较少见的临床情况。未分类高血压组未发现围产期问题。