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梅奥诊所早期乳腺癌治疗的变化:1988 - 1992年

Changes in the treatment of early breast cancer at the Mayo Clinic: 1988-1992.

作者信息

Grant C S

机构信息

Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Eur J Surg. 1996 Feb;162(2):93-6.

PMID:8639736
Abstract

OBJECTIVE

To investigate the temporal patterns in the surgical management of early (stages 0-2) breast cancer at Mayo Clinic between 1988 and 1992.

DESIGN

Retrospective study.

SETTING

Academic medical center, United States.

SUBJECTS

2551 patients with stage 0-2 primary breast cancer who underwent surgical treatment.

MAIN OUTCOME MEASURE

Change in the number of patients who underwent breast conserving surgery during the five year period.

RESULTS

The overall number of patients who underwent breast conserving surgery ranged from 73/498 (15%) in 1988 to 187/547 (34%) in 1992. When the patients who were ineligible to undergo breast conservation were subtracted from those who underwent mastectomy (leaving only those who chose mastectomy), the proportion nearly reached 50% in 1991, and breast conservation procedures exceeded mastectomies in 1992.

CONCLUSIONS

The majority of women primarily treated for early breast cancer during the five year period 1988-1992 undergo mastectomy. The reasons appear to be multifactorial, but a significant percentage are not eligible for breast conservation according to our criteria.

摘要

目的

调查1988年至1992年间梅奥诊所早期(0 - 2期)乳腺癌手术治疗的时间模式。

设计

回顾性研究。

地点

美国学术医疗中心。

研究对象

2551例接受手术治疗的0 - 2期原发性乳腺癌患者。

主要观察指标

五年期间接受保乳手术患者数量的变化。

结果

接受保乳手术的患者总数从1988年的73/498(15%)到1992年的187/547(34%)不等。当从接受乳房切除术的患者中减去不符合保乳条件的患者(仅留下选择乳房切除术的患者)时,1991年这一比例接近50%,1992年保乳手术超过了乳房切除术。

结论

在1988 - 1992年的五年期间,大多数主要接受早期乳腺癌治疗的女性接受了乳房切除术。原因似乎是多方面的,但根据我们的标准,相当比例的患者不符合保乳条件。

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