锌缺乏与腹泻和呼吸道疾病发病率增加的相关性——初步报告

Increased diarrhoeal and respiratory morbidity in association with zinc deficiency--a preliminary report.

作者信息

Bhandari N, Bahl R, Hambidge K M, Bhan M K

机构信息

Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Acta Paediatr. 1996 Feb;85(2):148-50. doi: 10.1111/j.1651-2227.1996.tb13981.x.

DOI:10.1111/j.1651-2227.1996.tb13981.x

PMID:8640039

Abstract

Plasma zinc levels, in a cohort of 116 children aged 12-59 months recently recovered from an episode of acute diarrhoea attending a community health clinic in an urban slum, were related to diarrhoeal and respiratory morbidity in the 3 month period following recovery. Children with low plasma zinc levels (< 60 micrograms dl-1) spent a significantly greater number of days with watery diarrhoea (rate ratio 1.69 (95% confidence intervals 1.03-2.78)), diarrhoea associated with fever (rate ratio 1.88 (95% confidence intervals 1.05-3.34)), and acute lower respiratory tract infections (rate ratio 2.69 (95% confidence intervals 1.64-4.38)).

摘要

在一个城市贫民窟社区卫生诊所，对116名年龄在12至59个月且近期刚从急性腹泻发作中康复的儿童进行研究，其血浆锌水平与康复后3个月内的腹泻和呼吸道疾病发病率相关。血浆锌水平低（<60微克/分升）的儿童出现水样腹泻的天数显著更多（率比1.69（95%置信区间1.03 - 2.78））、伴有发热的腹泻（率比1.88（95%置信区间1.05 - 3.34））以及急性下呼吸道感染（率比2.69（95%置信区间1.64 - 4.38））。