Trousseau's syndrome in association with ovarian carcinoma.
作者信息
Evans T R, Mansi J L, Bevan D H
机构信息
Department of Medical Oncology, St. George's Hospital Medical School, London, United Kingdom.
出版信息
Cancer. 1996 Jun 15;77(12):2544-9. doi: 10.1002/(SICI)1097-0142(19960615)77:12<2544::AID-CNCR18>3.0.CO;2-S.
BACKGROUND
The association of neoplastic disease and thromboembolic disorders was first recognized by Trousseau in 1865. Abnormalities of blood coagulation tests have been reported in the majority of patients with cancer, including ovarian carcinoma. However, Trousseau's syndrome has rarely been reported in women with ovarian carcinoma.
METHODS
A literature search for cases of Trousseau's syndrome in association with ovarian carcinoma was performed using the MEDLINE database. Case notes of patients with ovarian carcinoma treated at St. George's Hospital were reviewed and cases of Trousseau's syndrome identified.
RESULTS
We report a series of 4 cases of Trousseau's syndrome in association with ovarian carcinoma occurring over a 3- to 4-year period, and highlight the particular difficulties associated with the management of these thromboembolic effects.
CONCLUSIONS
Trousseau's syndrome can impair quality of life in patients with advanced ovarian carcinoma and enhanced anticoagulation regimens may be required for effective palliation.
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