Matsuoka R, Sawamura T, Yamada K, Yoshida M, Furutani Y, Ikura T, Shiraki T, Hoshikawa H, Shimada K, Tanzawa K, Masaki T
Department of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical College, Japan.
Cytogenet Cell Genet. 1996;72(4):322-4. doi: 10.1159/000134214.
The chromosomal localization of the human endothelin converting enzyme gene (ECE1) has been identified. Southern blot analysis of human genomic DNA from human x mouse somatic cell hybrids demonstrated that ECE1 maps to chromosome 1. Fluorescence in situ hybridization of a digoxigenin-labeled human ECE1 probe to normal human metaphase chromosomes showed that the gene is located within chromosome band 1p36.1.