Wyszko E, Barciszewski J, Barciszewska M
Institute of Biorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Nucleic Acids Symp Ser. 1995(33):53-5.
Eukaryotic transcription factor IIIA (TF IIIA) is know to activate specifically transcription of 5S rRNA gene. It also interacts with mature 5S rRNA. The best known TF IIIA has been purified from Xenopus laevis. Up to know this protein has not been isolated from plants. In this paper we show for the first time purification and properties of TF IIIA like protein from tulip (Tulipa whittalli). It shows 5S rRNA and 5S rRNA gene binding activity.
真核生物转录因子IIIA(TF IIIA)已知可特异性激活5S rRNA基因的转录。它还与成熟的5S rRNA相互作用。最知名的TF IIIA已从非洲爪蟾中纯化出来。到目前为止,这种蛋白质尚未从植物中分离出来。在本文中,我们首次展示了从郁金香(Tulipa whittalli)中纯化出的类似TF IIIA蛋白质的特性。它具有5S rRNA和5S rRNA基因结合活性。