维生素D3注射对孕鼠甲状腺滤泡旁细胞活性的影响。
Effects of vitamin D3 injection on activity of thyroid parafollicular cells in pregnant rats.
作者信息
Won J H, Taniguchi K, Sato R, Naito Y
机构信息
Department of Veterinary Internal Medicine, Faculty of Agriculture, Iwate University, Japan.
出版信息
J Vet Med Sci. 1996 Jan;58(1):75-6. doi: 10.1292/jvms.58.75.
Effects of vitamin D3 (VD3) injection on the activity of thyroid parafollicular cells (C cells) and calcium (Ca) metabolism were examined in rats of non-(NP), middle (MP) and late pregnancy (LP). At 3 days after injection, the average area of a C cell was significantly wider (P<0.01) in the VD3 groups than that in their control groups in NP, MP, and LP. On the otherhand, the plasma ca concentration in the VD3 groups decreased significantly (P<0.05) in comparison with that in their control groups in NP and LP, and tended to decrease in MP. These results suggest that injection of VD3 may accelerate the activity of C cells, which may result in the decrease of plasma Ca concentration in both non-pregnant and pregnant rats.
在非孕期（NP）、孕期中期（MP）和孕期晚期（LP）的大鼠中，研究了维生素D3（VD3）注射对甲状腺滤泡旁细胞（C细胞）活性和钙（Ca）代谢的影响。注射后3天，NP、MP和LP组中VD3组C细胞的平均面积比其对照组显著更宽（P<0.01）。另一方面，与NP和LP组的对照组相比，VD3组的血浆钙浓度显著降低（P<0.05），MP组有降低趋势。这些结果表明，注射VD3可能会加速C细胞的活性，这可能导致非孕和孕鼠血浆钙浓度降低。
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