Hatton F, Bouvier-Colle M H, Barois A, Imbert M C, Leroyer A, Bouvier S, Jougla E
Service d'Information sur les Causes Mèdicales de Dècés, SC8-INSERM, Le Vèsinet, France.
Acta Paediatr. 1995 Dec;84(12):1366-71. doi: 10.1111/j.1651-2227.1995.tb13570.x.
An enquiry into sudden infant death syndrome (SIDS) in 1987 furnished us with detailed epidemiological data for 281 cases that underwent a thorough post-mortem examination. This analysis uses these data to evaluate the role the autopsy plays in explaining sudden death. The cases were classified into three diagnostic groups: explained causes of death (group 1), unexplained deaths with anomalies (group 2), and no anomaly (group 3). These 281 cases show the three essential features that characterize SIDS: over-representation of males, increased deaths during the second and third months of life, and increased deaths during winter. The autopsy examination revealed that many of these deaths had a medical explanation. Almost half were assigned to group 1. At the time of autopsy, no precise pathology could be diagnosed for 147 deaths; of these, 140 showed histological anomalies. There were only seven sudden deaths for which no abnormal sign was evident at the autopsy. These results are compared with those of similar studies and discussed in connection with three factors: the initial selection of cases, the nature and degree of the investigations, and the possible interpretations of the symptoms uncovered.
1987年对婴儿猝死综合征（SIDS）的一项调查为我们提供了281例经过全面尸检的详细流行病学数据。本分析利用这些数据评估尸检在解释猝死方面所起的作用。这些病例被分为三个诊断组：死因明确（第1组）、有异常的不明死因（第2组）和无异常（第3组）。这281例病例显示了SIDS的三个基本特征：男性比例过高、出生后第二和第三个月死亡人数增加以及冬季死亡人数增加。尸检显示，这些死亡中有许多都有医学解释。几乎一半被归入第1组。尸检时，147例死亡无法诊断出确切的病理学原因；其中140例显示有组织学异常。尸检时仅有7例猝死未发现异常迹象。将这些结果与类似研究的结果进行了比较，并结合三个因素进行了讨论：病例的初始选择、调查的性质和程度以及对所发现症状的可能解释。
