Martinez-Taboada V M, Alonso R B, Armona J, Fernandez-Sueiro J L, Gonzalez Vela C, Rodriguez-Valverde V
Rheumatology Division, Hospital Universitario M. Valdecilla, Facultad de Medicina, Universidad de Cantabria, Santander, Spain.
Lupus. 1996 Feb;5(1):74-6. doi: 10.1177/096120339600500114.
Severe mononeuritis multiplex in systemic lupus erythematosus (SLE) is quite rare and almost always accompanied by evidence of active disease in other organs, although occasionally it may be the presenting feature of the disease. We describe here two patients with SLE who presented a severe mononeuritis multiplex secondary to a necrotizing vasculitis which respond successfully to therapy with intravenous cyclophosphamide, and review the literature of similar cases.
系统性红斑狼疮（SLE）伴发的严重多发性单神经炎相当罕见，几乎总是伴有其他器官活动性病变的证据，尽管偶尔它可能是该疾病的首发特征。我们在此描述了两名SLE患者，他们继发于坏死性血管炎出现严重的多发性单神经炎，经静脉注射环磷酰胺治疗后成功缓解，并回顾了类似病例的文献。
