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大肠杆菌中RpoS对稳定期末期表达基因的调控

RpoS-dependent regulation of genes expressed at late stationary phase in Escherichia coli.

作者信息

Talukder A A, Yanai S, Nitta T, Kato A, Yamada M

机构信息

Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Japan.

出版信息

FEBS Lett. 1996 May 20;386(2-3):177-80. doi: 10.1016/0014-5793(96)00426-7.

Abstract

We have identified 6 Escherichia coli genomic genes, including 4 new genes, responsive to the stationary phase. One of them was regulated positively by RpoS at the stationary phase, and the remaining 5 negatively at a late stationary phase, all of them responding to multiple environmental stresses. Nucleotide sequences as well as such multiple responses revealed that those genes may have more than one overlapping-promoter recognized by different sigma-factors which regulate gene expressions during their cell growth.

摘要

我们已经鉴定出6个大肠杆菌基因组基因,其中包括4个新基因,它们对稳定期有反应。其中一个基因在稳定期受到RpoS的正调控,其余5个在稳定期末期受到负调控,所有这些基因都对多种环境胁迫有反应。核苷酸序列以及这种多重反应表明,这些基因可能有一个以上被不同σ因子识别的重叠启动子,这些σ因子在细胞生长过程中调节基因表达。

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