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[激光心肌血运重建术(LTMR)的现状与21世纪]

[Current status and 21 century in the laser transmyocardial revascularization (LTMR)].

作者信息

Okada M

机构信息

Kobe University School of Medicine, Department of Surgery, Division II, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1996 Mar;97(3):234-9.

PMID:8649335
Abstract

Recently, much attention has been paid to promote endovascular intervention for the patients with ischemic heart disease and occlusive peripheral arterial disease. There are a few patients for whom coronary artery bypass grafting and repeated PTCA can not be carried out, because small branches or diffuse stenoses of the coronary arteries. To resolve these problems author tried to supply arterial blood from the left ventricle into the ischemic myocardium through new channels created into the myocardium by CO2 laser. Consequently, it could be clarified that this procedure could be hemodynamically, or histologically used as an alternative transmyocardial revascularization (TMR) by laser. Finally, this TMR was clinically employed in 1985. Mechanism, technique and its results of TMR are discussed in detail.

摘要

最近,人们十分关注促进对缺血性心脏病和闭塞性外周动脉疾病患者进行血管内介入治疗。有一些患者由于冠状动脉小分支或弥漫性狭窄而无法进行冠状动脉旁路移植术和重复经皮冠状动脉腔内血管成形术(PTCA)。为了解决这些问题,作者尝试通过二氧化碳激光在心肌中创建新通道,将左心室的动脉血供应到缺血心肌中。因此,可以明确的是,该手术在血流动力学或组织学上可作为激光心肌血运重建术(TMR)的替代方法。最终,这种TMR于1985年应用于临床。本文将详细讨论TMR的机制、技术及其结果。

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