Greenberg S M, Finklestein S P, Schaefer P W
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
Neurology. 1996 Jun;46(6):1751-4. doi: 10.1212/wnl.46.6.1751.
Based on the pathologic observation that severe cerebral amyloid angiopathy is often accompanied by multiple petechial hemorrhages, we prospectively obtained gradient-echo MRI on 15 elderly patients with lobar hemorrhage on CT. Nine of the 15 demonstrated accompanying petechial hemorrhages restricted to the cortical or corticosubcortical regions. No similar lesions were present on gradient-echo MRI in 10 elderly control patients. These findings suggest that cerebral amyloid angiopathy might be neuroradiologically diagnosed and staged during life.
基于严重脑淀粉样血管病常伴有多发性瘀点样出血的病理学观察,我们前瞻性地对15例CT显示脑叶出血的老年患者进行了梯度回波MRI检查。15例患者中有9例显示伴有局限于皮质或皮质下皮质区域的瘀点样出血。10例老年对照患者的梯度回波MRI未发现类似病变。这些发现提示脑淀粉样血管病可能在生前通过神经放射学进行诊断和分期。