Cousins L M, Teplick F B, Poeltler D M
Mary Birch Hospital for Women, Sharp Memorial, San Diego, California, USA.
Obstet Gynecol. 1996 Jun;87(6):912-6. doi: 10.1016/0029-7844(96)00043-9.
To 1) characterize pre-cesarean blood bank testing, 2) describe the transfusion experience in a large series of cesarean patients, and 3) evaluate safety and cost implications of a "hold clot" order for patients at low risk for transfusion.
A review of 1111 consecutive cesarean patients used computerized perinatal and blood bank data bases and a detailed chart review of all cross-matched patients. Information collected included indications for cesarean and transfusion, etiology of hemorrhage, transfusion number and type, admission and lowest hemoglobin level, and information regarding the events leading to transfusion. A blinded review of the cross-matched patient's information assessed whether a cross-match was appropriate or could have been replaced safely by a "hold clot" (current clot tube in blood bank) order.
Nineteen patients (1.7%) were transfused. The only patients requiring a transfusion were diagnosed with placenta previa, placenta accreta, anemia, preeclampsia/hemolysis, elevated liver enzymes, low platelets (HELLP syndrome), or hemorrhage. A comparison of two blood banking approaches (routine pre-cesarean type and screen testing versus a "hold clot" order for cesarean patients at low risk for transfusion) indicated that the latter would reduce costs by $45 per cesarean, or $95,000 annually.
The incidence of transfusion was low (1.7%) and associated with specific diagnoses (previa, accreta, anemia, preeclampsia/HELLP, or hemorrhage). The data support the replacement of pre-cesarean type and screen testing with a "hold clot" order for patients at low risk for transfusion with negative prenatal antibody screen. This approach is safe and would reduce cost substantially.
1)描述剖宫产术前血库检测情况;2)描述大量剖宫产患者的输血经历;3)评估对输血低风险患者下达“保留凝血块”医嘱的安全性及成本影响。
回顾1111例连续剖宫产患者,使用计算机化围产期和血库数据库,并对所有交叉配血患者进行详细病历审查。收集的信息包括剖宫产和输血指征、出血病因、输血量和类型、入院时及最低血红蛋白水平,以及导致输血的相关事件信息。对交叉配血患者信息进行盲法审查,以评估交叉配血是否恰当,或者是否可以通过“保留凝血块”(血库当前的凝血试管)医嘱安全替代。
19例患者(1.7%)接受了输血。仅诊断为前置胎盘、胎盘植入、贫血、先兆子痫/溶血、肝酶升高、血小板减少(HELLP综合征)或出血的患者需要输血。对两种血库处理方法(常规剖宫产血型及筛查检测与对输血低风险剖宫产患者下达“保留凝血块”医嘱)进行比较,结果表明后者每例剖宫产可降低成本45美元,或每年降低95,000美元。
输血发生率较低(1.7%),且与特定诊断(前置胎盘、胎盘植入、贫血、先兆子痫/HELLP或出血)相关。数据支持对产前抗体筛查阴性的输血低风险患者,用“保留凝血块”医嘱替代剖宫产术前血型及筛查检测。这种方法安全且可大幅降低成本。