用地高辛免疫Fab片段治疗地高辛中毒
[Digoxin poisoning treated with Digibind].
作者信息
Andersen J B, Sørensen B U, Andersen L I
机构信息
Thoraxkirurgisk afdeling T, Odense Universitetshospital.
出版信息
Ugeskr Laeger. 1996 Apr 15;158(16):2262-4.
A case of digoxin intoxication and hyperkalaemia causing cardiac arrest in a 63-year-old female who had undergone cardiac surgery is presented. Symptomatic treatment was given. However, as the patient continued to be unstable we introduced digoxin Fab-antibody in the treatment. The patient changed her heart rhythm from atrioventricular conduction block to atrial fibrillation within a few minutes and recovered later on. The pharmacology and the indications for treatment with digoxin Fab-antibody fragments are discussed.
本文报告了一例63岁接受心脏手术的女性患者，因地高辛中毒和高钾血症导致心脏骤停。给予了对症治疗。然而，由于患者持续不稳定，我们在治疗中引入了地高辛Fab抗体。患者在几分钟内心律从房室传导阻滞转变为心房颤动，随后康复。文中讨论了地高辛Fab抗体片段的药理学及治疗指征。
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