Karagas M R, Lu-Yao G L, Barrett J A, Beach M L, Baron J A
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH 03755-3861, USA.
Am J Epidemiol. 1996 Apr 1;143(7):677-82. doi: 10.1093/oxfordjournals.aje.a008800.
To explore potential etiologic differences in the two major types of hip fracture, the authors computed the incidence rates of fractures of the femoral neck and trochanteric region of the proximal femur using a 5 percent sample of the US Medicare population aged 65-99 years. For the period they examined, July 1, 1986, through June 30, 1990, the rates of both hip fracture types increased with age in all race and sex categories. The proportion of hip fractures that occurred in the trochanteric region rose steeply with age among white women, but not among black women, white men, or black men. Within the United States, a north-to-south gradient in rates of both fracture types was observed among women, while no clear pattern was found for men. These findings raise the possibility of etiologic differences in the two fracture types, and the results provide further evidence of sex and racial differences in the risk of osteoporotic fractures.
为探究两种主要类型髋部骨折潜在的病因差异,作者利用美国医疗保险中65 - 99岁人群5%的样本,计算了股骨颈骨折和股骨近端转子区骨折的发病率。在他们所研究的1986年7月1日至1990年6月30日期间,所有种族和性别的两类髋部骨折发病率均随年龄增长而上升。转子区髋部骨折的比例在白人女性中随年龄急剧上升,但在黑人女性、白人男性或黑人男性中并非如此。在美国,女性中两类骨折发病率均呈现出从北到南的梯度变化,而男性中未发现明显规律。这些发现增加了两类骨折病因存在差异的可能性,研究结果进一步证明了骨质疏松性骨折风险存在性别和种族差异。