用¹²⁵I标记的葡萄球菌蛋白A检测血小板结合的IgG
Detection of platelet-bound IgG with 125I-labelled staphylococcal protein A.
出版信息
Med Biol. 1977 Apr;55(2):112-4.
PMID:865154
Abstract
125I-labelled protein A from Staphylococcus aureus binds effectively with platelets coated either with specific antibodies or with unrelated immune complexes. Protein A can therefore be used to measure these serum factors. A prior dilution of the serum enhances markedly the reactivity of the serum in idopathic thrombocytopenic purpura. This may be due to abolished inhibition exerted by normal monomeric IgG.
摘要
来自金黄色葡萄球菌的125I标记蛋白A能有效地与包被有特异性抗体或不相关免疫复合物的血小板结合。因此，蛋白A可用于检测这些血清因子。血清预先稀释可显著增强特发性血小板减少性紫癜患者血清的反应性。这可能是由于正常单体IgG所施加的抑制作用被消除。
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