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[HIV 疾病中的上消化道内镜检查]

[Endoscopy of the upper gastrointestinal tract in HIV disease].

作者信息

Caca K, Zietz C, Bogner J R, Goebel F D, Zoller W G

机构信息

Klinikum Innenstadt, Ludwig-Maximilians-Universität München, Deutschland.

出版信息

Bildgebung. 1995 Dec;62(4):244-51.

PMID:8652996
Abstract

Gastrointestinal (GI) symptoms are part of the most frequent complaints in HIV disease. A methodical effort is required to identify treatable syndromes. Progressive immunodeficiency is associated with increased prevalence of opportunistic or non-opportunistic infections and neoplasms. Dysphagia and odynophagia, in the majority due to candida esophagitis, are best evaluated by endoscopy. In the presence of diarrhea, upper GI endoscopy is indicated if evaluations of stool and endoscopy of the lower GI tract are negative and may uncover proximal small-bowel infection by Cryptosporidium, Microsporidium or Mycobacterium avium. HIV-associated neoplasias (Kaposi's sarcoma, non-Hodgkin lymphomas), not rarely affecting the upper GI tract and sometimes leading to obstruction or bleeding, are reliably diagnosed only by endoscopy. Since visible lesions mostly are nonspecific and normal-appearing mucosa may harbor pathogens, biopsies for pathology and cultures are crucial for correct diagnosis in GI diseases of HIV-infected patients.

摘要

胃肠道(GI)症状是HIV疾病中最常见的主诉之一。需要有条不紊地努力来识别可治疗的综合征。进行性免疫缺陷与机会性或非机会性感染及肿瘤的患病率增加有关。吞咽困难和吞咽痛多数由念珠菌性食管炎引起,最好通过内镜检查进行评估。出现腹泻时,如果粪便检查和下消化道内镜检查均为阴性,则需进行上消化道内镜检查,其可能发现近端小肠隐孢子虫、微孢子虫或鸟分枝杆菌感染。HIV相关肿瘤(卡波西肉瘤、非霍奇金淋巴瘤)不少见,可累及上消化道,有时导致梗阻或出血,仅通过内镜检查才能可靠诊断。由于可见病变大多是非特异性的,外观正常的黏膜也可能藏有病原体,因此病理活检和培养对于HIV感染患者胃肠道疾病的正确诊断至关重要。

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