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使用1毫米准直器测试立体定向放射治疗的准确性。

Use of a 1 mm collimator to test the accuracy of stereotactic radiotherapy.

作者信息

Tsai J S, Curran B H, Sternick E S, Engler M J

机构信息

Department of Radiation Oncology, Tufts University School of Medicine, Boston, MA, USA.

出版信息

Int J Radiat Oncol Biol Phys. 1996 Jun 1;35(3):579-86. doi: 10.1016/s0360-3016(96)80021-6.

Abstract

PURPOSE

To develop a method of measuring locations of the center of dose in stereotactic radiotherapy relative to the center of the target, and thereby obtain a test of the accuracy of stereotactic radiotherapy (SRT).

METHODS AND MATERIALS

An insert was mounted in an SRT collimator on a 6 MV linear accelerator to provide a photon beam approximately 1 mm in diameter at isocenter, and a method of measuring radiation center coordinates of arced SRT beams. To simulate a small intracranial target, two halves of a Barium paste column were embedded in two adjacent slabs of a humanoid phantom. A film was placed between the slabs to image the radiation relative to the target center. A surgical head ring and computerized tomography (CT) localizer were attached to the phantom and CT scans were obtained. The scans were entered in a three-dimensional computerized treatment-planning system and radiation isocenter coordinates determined by iteratively moving the 90% isodose surface center of arced beam dose distributions to coincide with the target center. The phantom was bolted to an SRT floorstand with isocenter coordinates obtained from the treatment plan, and then irradiated in two sets of experiments. The first set applied five 1 mm noncoplanar arced beams with and without offsets of the planned coordinates in the transverse plane. The second set applied one large transverse arc coplanar to the film with and without offsets in the craniocaudal direction. Irradiations with coordinate offsets tested the sensitivity of the method. Films were developed and digitized with a high resolution film scanner to measure the location of the radiation relative to the target center.

RESULTS AND CONCLUSION

The radiation center was found from 0.0 to 0.3 mm of the target center, within requirements of our clinical quality assurance program. The measurement and evaluation of coincidence of radiation and target centers are, thus, proposed as elements of radiosurgery facility acceptance and annual quality assurance.

摘要

目的

开发一种测量立体定向放射治疗中剂量中心相对于靶区中心位置的方法,从而获得立体定向放射治疗(SRT)准确性的测试方法。

方法和材料

在6兆伏直线加速器的SRT准直器上安装一个插入物,以在等中心处提供直径约1毫米的光子束,以及一种测量弧形SRT束辐射中心坐标的方法。为模拟一个小的颅内靶区,将两半钡糊柱嵌入人形模体的两个相邻平板中。在平板之间放置一张胶片,以成像相对于靶区中心的辐射。将手术头环和计算机断层扫描(CT)定位器连接到模体上,并进行CT扫描。将扫描数据输入三维计算机治疗计划系统,并通过迭代移动弧形束剂量分布的90%等剂量面中心使其与靶区中心重合来确定辐射等中心坐标。将模体用螺栓固定在具有从治疗计划中获得的等中心坐标的SRT落地架上,然后在两组实验中进行照射。第一组施加五条1毫米的非共面弧形束,在横断面方向上有和没有计划坐标的偏移。第二组施加一条与胶片共面的大的横向弧形束,在头尾方向上有和没有偏移。有坐标偏移的照射测试了该方法的敏感性。对胶片进行显影并用高分辨率胶片扫描仪进行数字化处理,以测量辐射相对于靶区中心的位置。

结果与结论

发现辐射中心位于距靶区中心0.0至0.3毫米范围内,符合我们临床质量保证计划的要求。因此,建议将辐射中心与靶区中心重合性的测量和评估作为放射外科设备验收和年度质量保证的内容。

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