甲酚甲醛作为一种用于乳牙牙髓切断术的药物的发展历程。
The development of formocresol as a medicament for primary molar pulpotomy procedures.
作者信息
Nunn J H, Smeaton I, Gilroy J
机构信息
Department of Child Dental Health, Dental School, Newcastle Upon Tyne.
出版信息
ASDC J Dent Child. 1996 Jan-Feb;63(1):51-3.
The development of formocresol as a pulpotomy medicament is charted from the 19th Century to the present day. While the solution has come in and out of vogue, few agents can seriously challenge its efficacy. Doubts about its toxicity, mutagenicity, and carcinogenicity have led, however, to a call for a more dilute formulation as well as a review of alternative medicaments. Problems arise in deriving an appropriate formula for a dilute version from existing formulations, which appear to have misinterpreted the concentration of constituents in the original solution.
从19世纪至今，甲酚甲醛作为一种牙髓切断术药物的发展历程被一一记录。尽管这种溶液曾流行一时，之后又不再受青睐，但很少有药剂能在疗效上对其构成严重挑战。然而，对其毒性、致突变性和致癌性的疑虑，引发了对更稀释配方的需求，以及对替代药物的重新审视。从现有配方中推导合适的稀释配方时出现了问题，因为现有配方似乎误解了原始溶液中成分的浓度。
Zotero 插件