Chavant L, Le Bars J, Sancholle M
Mycopathologia. 1977 Apr 29;60(3):151-5. doi: 10.1007/BF00448407.
Aspergillus versicolor is cultivated in a synthetic medium for 22 days. Bioproduction of lipids and sterigmatocystin are compared. The fatty acids of the neutral lipid and polar lipids fractions are mainly: C 16:0, C 18:0, C 18:1, C 18:2, C 18:3. Maximal yields of dry weight, neutral lipids and sterigmatocystin occur, respectively, on the 4th, the 7th and the 20th days. These results and their comparison with other works emphasize that a fall of concentration in lipids precedes the phase of highest concentration in secondary metabolites of polyketide type; it appears that fats and particularly palmitic acid are present in biogenesis of these derivatives.
杂色曲霉在合成培养基中培养22天。比较脂质和柄曲霉素的生物合成。中性脂质和极性脂质部分的脂肪酸主要为:C 16:0、C 18:0、C 18:1、C 18:2、C 18:3。干重、中性脂质和柄曲霉素的最大产量分别出现在第4天、第7天和第20天。这些结果以及它们与其他研究的比较强调,脂质浓度的下降先于聚酮类次生代谢物最高浓度阶段;似乎脂肪尤其是棕榈酸在这些衍生物的生物合成中存在。