Watson P, Voss L, Barber C, Aickin R, Bremner D, Lennon D
Starship Children's Health, Microbiology Laboratory Services, Auckland Hospital.
N Z Med J. 1996 May 24;109(1022):182-4.
To determine the microbiology of chronic otitis media with effusion in a group of Auckland children. To determine the antimicrobial sensitivities of isolated bacterial pathogens to commonly used antibiotics for this condition.
A descriptive study recruiting subjects from otherwise well children with chronic otitis media with effusion having insertion of ventilation tubes at Starship Children's Health, Auckland. Tympanocentesis was performed, the middle ear aspirate cultured and antimicrobial sensitivities obtained.
Sixty seven children (11mo to 8yr) with chronic otitis media with effusion had tympanocentesis of 105 ears. 38/105 (36%) of the middle ear aspirate cultures were positive. Forty nine organisms were isolated with 10 ears having two or more different bacteria identified. Isolated were 17 Haemophilus influenzae (16 nontype b and 1 type b), 13 Moraxella catarrhalis, nine Streptococcus pneumoniae and 10 'others'. All S pneumoniae(9/9), most H influenzae(14/17) and no M catarrhalis(0/13) were sensitive to amoxycillin. More than 80% of subjects had either a sterile effusion or an organism sensitive to amoxycillin or cotrimoxazole.
Middle ear effusions were culture positive in a third of cases of chronic otitis media with effusion. The commonest organisms were H influenzae nontype b, M catarrhalis and S pneumoniae. This is similar to reports from other countries. Sensitivity data obtained supports the continued recommendation of amoxycillin or cotrimoxazole as first line therapy for the antimicrobial treatment of this condition.
确定奥克兰一组儿童慢性分泌性中耳炎的微生物情况。确定分离出的细菌病原体对该病症常用抗生素的抗菌敏感性。
一项描述性研究，招募奥克兰星舰儿童医院患有慢性分泌性中耳炎并接受通气管植入术的健康儿童作为研究对象。进行鼓膜穿刺术，对中耳吸出物进行培养并获得抗菌敏感性结果。
67名（年龄11个月至8岁）患有慢性分泌性中耳炎的儿童接受了105耳的鼓膜穿刺术。105份中耳吸出物培养物中有38份（36%）呈阳性。共分离出49种微生物，10耳检出两种或更多种不同细菌。分离出17株流感嗜血杆菌（16株非b型和1株b型）、13株卡他莫拉菌、9株肺炎链球菌和10株“其他细菌”。所有肺炎链球菌（9/9）、大多数流感嗜血杆菌（14/17）和无卡他莫拉菌（0/13）对阿莫西林敏感。超过80%的研究对象中耳积液无菌或含有对阿莫西林或复方新诺明敏感的微生物。
在三分之一的慢性分泌性中耳炎病例中，中耳积液培养呈阳性。最常见的微生物是非b型流感嗜血杆菌、卡他莫拉菌和肺炎链球菌。这与其他国家的报告相似。获得的敏感性数据支持继续推荐阿莫西林或复方新诺明作为该病症抗菌治疗的一线疗法。
