Ganowicz J, Milewska-Bobula B, Jezierska-Kasprzyk K, Witwicki J M
Oddział Patologii Norworodka i Niemowlecia Centrum Zdrowia Dziecka w Warszawie.
Pediatr Pol. 1995 Mar;70(3):249-53.
One of the most critical problems of neonatology persistent pulmonary hypertension in the newborn, is discussed. This syndrome is characterized by increased resistance in pulmonary vessels leading to hypertension in pulmonary arteries and a recurrence of R > L shunting at the ductus arteriosus and foramen ovale. This leads to deep hypoxia and hypoxemia. It is most important to rule out a congenital cyanotic heart defect in the differential diagnosis. The aim of the treatment is to establish normal ventilation and intrapulmonary shunting as well as to control the symptoms leading to pulmonary hypertension that persist over time. The goal preceding treatment should be to determine the initial cause of the persistent pulmonary hypertension.
本文讨论了新生儿科最关键的问题之一——新生儿持续性肺动脉高压。该综合征的特征是肺血管阻力增加,导致肺动脉高压,并在动脉导管和卵圆孔处反复出现右向左分流。这会导致严重的低氧血症。在鉴别诊断中,最重要的是排除先天性青紫型心脏缺陷。治疗的目的是建立正常的通气和肺内分流,以及控制随着时间推移持续存在的导致肺动脉高压的症状。治疗前的目标应该是确定持续性肺动脉高压的初始病因。