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[具有用于开发新一代疫苗潜力的黏膜免疫]

[Mucosal immunity with implications for use in developing a new generation of vaccines].

作者信息

Osek J, Truszczyński M

机构信息

Zakład Mikrobiologii Państwowego Instytutu Weterynaryjnego w Puławach.

出版信息

Postepy Hig Med Dosw. 1995;49(4):469-86.

PMID:8657643
Abstract

The mucosal immune system is a very important component of the body's defence against pathogenic organisms, especially those responsible for enteric infections. On the basis of the concept of a common mucosal immune system, there is currently much interest in the possibility of developing oral vaccines against respiratory and urogenital tracts infections. There is also a great need to develop strategies for enhancing delivery of antigens to the mucosal immune system as well as to identify mucosa-active immunostimulating adjuvants.

摘要

黏膜免疫系统是机体抵御致病生物,尤其是那些引发肠道感染的致病生物的重要组成部分。基于共同黏膜免疫系统的概念,目前人们对开发针对呼吸道和泌尿生殖道感染的口服疫苗的可能性非常感兴趣。此外,迫切需要制定策略来增强抗原向黏膜免疫系统的递送,并鉴定具有黏膜活性的免疫刺激佐剂。

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