• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[具有用于开发新一代疫苗潜力的黏膜免疫]

[Mucosal immunity with implications for use in developing a new generation of vaccines].

作者信息

Osek J, Truszczyński M

机构信息

Zakład Mikrobiologii Państwowego Instytutu Weterynaryjnego w Puławach.

出版信息

Postepy Hig Med Dosw. 1995;49(4):469-86.

PMID:8657643
Abstract

The mucosal immune system is a very important component of the body's defence against pathogenic organisms, especially those responsible for enteric infections. On the basis of the concept of a common mucosal immune system, there is currently much interest in the possibility of developing oral vaccines against respiratory and urogenital tracts infections. There is also a great need to develop strategies for enhancing delivery of antigens to the mucosal immune system as well as to identify mucosa-active immunostimulating adjuvants.

摘要

黏膜免疫系统是机体抵御致病生物,尤其是那些引发肠道感染的致病生物的重要组成部分。基于共同黏膜免疫系统的概念,目前人们对开发针对呼吸道和泌尿生殖道感染的口服疫苗的可能性非常感兴趣。此外,迫切需要制定策略来增强抗原向黏膜免疫系统的递送,并鉴定具有黏膜活性的免疫刺激佐剂。

相似文献

1
[Mucosal immunity with implications for use in developing a new generation of vaccines].[具有用于开发新一代疫苗潜力的黏膜免疫]
Postepy Hig Med Dosw. 1995;49(4):469-86.
2
Mucosal immunity and vaccination.黏膜免疫与疫苗接种。
FEMS Microbiol Immunol. 1991 Dec;4(1):1-9. doi: 10.1111/j.1574-6968.1991.tb04964.x.
3
Mucosal immunization against respiratory bacterial pathogens.针对呼吸道细菌病原体的黏膜免疫
Expert Rev Vaccines. 2003 Aug;2(4):551-60. doi: 10.1586/14760584.2.4.551.
4
Induction of a mucosal immune response by oral immunization. An overview.通过口服免疫诱导黏膜免疫反应。综述。
Z Erkr Atmungsorgane. 1991;177(1-2):20-34.
5
Transcutaneous immunization with a novel lipid-based adjuvant protects against Chlamydia genital and respiratory infections.使用新型脂质佐剂进行经皮免疫可预防衣原体性生殖道和呼吸道感染。
Vaccine. 2009 Oct 19;27(44):6217-25. doi: 10.1016/j.vaccine.2009.08.001. Epub 2009 Aug 19.
6
Mucosal delivery of vaccines in domestic animals.家畜疫苗的黏膜给药
Vet Res. 2006 May-Jun;37(3):487-510. doi: 10.1051/vetres:2006012. Epub 2006 Apr 14.
7
Routes of immunization and antigen delivery systems for optimal mucosal immune responses in humans.用于人类最佳黏膜免疫反应的免疫途径和抗原递送系统。
Behring Inst Mitt. 1997 Feb(98):33-43.
8
A Forum guide to mucosal immunization.黏膜免疫接种论坛指南。
CVI Forum. 1994 Apr(6):2-3.
9
In defense of mucosal surfaces. Development of novel vaccines for IgA responses protective at the portals of entry of microbial pathogens.黏膜表面的防御。开发针对在微生物病原体进入门户起保护作用的IgA应答的新型疫苗。
Infect Dis Clin North Am. 1990 Jun;4(2):315-41.
10
New generation of mucosal adjuvants for the induction of protective immunity.用于诱导保护性免疫的新一代黏膜佐剂。
Rev Med Virol. 2003 Sep-Oct;13(5):293-310. doi: 10.1002/rmv.398.

引用本文的文献

1
Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain.经舌下免疫接种编码 SARS-CoV 刺突蛋白的重组腺病毒可诱导全身和黏膜免疫,而不会使病毒转向大脑。
Virol J. 2012 Sep 21;9:215. doi: 10.1186/1743-422X-9-215.