Zmonarski S C, Klinger M, Puziewicz-Zmonarska A
Katedria i Klinika Nefrologii Akademii Medycznej we Wrocławiu.
Postepy Hig Med Dosw. 1995;49(4):487-512.
Up to day the pathogenesis of immune deficiency in chronic renal failure have not been clearly elucidated. There is no agreement where is situated the primary disturbance that makes that category of patients more susceptible to infections and neoplasms. The views presented in this paper seem to shift the balance toward multifactor theory. Possible influence of many biochemical abnormalities and effect of renal replacement therapies on main elements of immune system are discussed.
迄今为止,慢性肾衰竭免疫缺陷的发病机制尚未完全阐明。对于使这类患者更易感染和患肿瘤的原发性紊乱所在位置,尚无定论。本文提出的观点似乎使天平向多因素理论倾斜。文中讨论了许多生化异常的可能影响以及肾脏替代疗法对免疫系统主要成分的作用。