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蛛网膜下腔出血后颅内动脉瘤的磁共振血管造影

[Magnetic resonance angiography of intracranial aneurysms after subarachnoid hemorrhage].

作者信息

Felber S, Bösch S, Henkes H, Twerdy K, Judmaier W, Attlmayr G, Terstegge K, Aichner F

机构信息

Institut für Magnetresonanztomographie, Universitätskliniken, Innsbruck.

出版信息

Radiologe. 1995 Nov;35(11):822-9.

PMID:8657884
Abstract

Magnetic resonance angiography is now commercially available for a variety of scanners and is being increasingly applied in the diagnosis of cerebrovascular disorders. Considering the clinical consequences, especially in intracranial aneurysms, studies to determine the sensitivity and specificity of the method are essential. Here we report our experience with a 3D-FISH time-of-flight magnetic resonance angiography protocol in 52 patients who have suffered an acute subarachnoid hemorrhage. In 26 of the 52 patients, conventional angiography identified 31 aneurysms (3-20 mm) that were confirmed during surgery or autopsy. Magnetic resonance angiography correctly identified 28 of the 31 aneurysms (sensitivity 90.3%) and missed one ruptured (3 mm) and two incidental aneurysms (3 mm) in patients with multiple aneurysms. The sensitivity for a ruptured aneurysm was 96%. The 26 patients who suffered subarachnoid hemorrhage without evidence of an intracranial aneurysm on repeated angiography served as a control group. Magnetic resonance angiography revealed no false-positive findings, resulting in a specificity of 100%. In correlation with the literature, we conclude that magnetic resonance angiography is not sensitive enough for the management of acute subarachnoid hemorrhage. However, the method provides important complementary information for definition of the bleeding site in patients with multiple aneurysms. In addition, the calculation of projections not possible with conventional angiography can aid surgical planning. Since only very small aneurysms were missed by magnetic resonance angiography, the sensitivity seems appropriate to screen asymptomatic patients who are at risk for intracranial aneurysms.

摘要

磁共振血管造影目前在各种扫描仪上均可商业应用,并越来越多地用于脑血管疾病的诊断。考虑到临床后果,尤其是颅内动脉瘤的情况,确定该方法的敏感性和特异性的研究至关重要。在此,我们报告了我们对52例急性蛛网膜下腔出血患者采用三维快速成像稳态进动序列磁共振血管造影方案的经验。在这52例患者中,有26例经传统血管造影发现了31个动脉瘤(3 - 20毫米),这些动脉瘤在手术或尸检中得到证实。磁共振血管造影正确识别出了31个动脉瘤中的28个(敏感性为90.3%),在患有多个动脉瘤的患者中漏诊了1个破裂的(3毫米)和2个偶然发现的动脉瘤(3毫米)。对破裂动脉瘤的敏感性为96%。26例经反复血管造影未发现颅内动脉瘤证据的蛛网膜下腔出血患者作为对照组。磁共振血管造影未发现假阳性结果,特异性为100%。与文献相关内容对比,我们得出结论,磁共振血管造影对于急性蛛网膜下腔出血的处理敏感性不够。然而,该方法为患有多个动脉瘤的患者确定出血部位提供了重要的补充信息。此外,常规血管造影无法进行的投影计算有助于手术规划。由于磁共振血管造影仅漏诊了非常小的动脉瘤,其敏感性似乎适合用于筛查有颅内动脉瘤风险的无症状患者。

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