Kujat C, Hagen T, Feiden W
Institut für Neuroradiologie, Universität des Saarlandes, Homburg/Saar.
Radiologe. 1995 Nov;35(11):834-7.
Creutzfeldt-Jakob disease (CJD) is a rare, but fatal and transmissible brain disease. The clinical diagnosis is based upon progressing dementia, myoclonic jerks and characteristic EEG changes, but it is difficult to diagnose and not only in the early phase of the disease. Cerebral biopsy is reserve for individual selected cases and contested because of the danger of contamination from instruments and potential transmission. We report three patients with histologically confirmed CJD and confirm that MRI is a valuable tool for the diagnosis of this disease.
克雅氏病（CJD）是一种罕见但致命且可传播的脑部疾病。临床诊断基于进行性痴呆、肌阵挛性抽搐和特征性脑电图变化，但这种疾病难以诊断，尤其是在疾病早期。脑活检仅适用于个别选定病例，且因存在器械污染和潜在传播风险而颇具争议。我们报告了三例经组织学确诊为克雅氏病的患者，并证实磁共振成像（MRI）是诊断该疾病的一种有价值的工具。
