Wang G, Tanaka K, Tanifuji M
Laboratory for Neural Information Processing, Frontier Research Program, Institute of Physical and Chemical Research (RIKEN), Kagoshima University, Japan.
Science. 1996 Jun 14;272(5268):1665-8. doi: 10.1126/science.272.5268.1665.
To investigate the functional organization of object recognition, the technique of optical imaging was applied to the primate inferotemporal cortex, which is thought to be essential for object recognition. The features critical for the activation of single cells were first determined in unit recordings with electrodes. In the subsequent optical imaging, presentation of the critical features activated patchy regions around 0.5 millimeters in diameter, covering the site of the electrode penetration at which the critical feature had been determined. Because signals in optical imaging reflect average neuronal activities in the regions, the result directly indicates the regional clustering of cells responding to similar features.
为了研究物体识别的功能组织，将光学成像技术应用于灵长类动物的颞下皮质，该区域被认为对物体识别至关重要。首先在使用电极的单位记录中确定激活单个细胞的关键特征。在随后的光学成像中，呈现关键特征会激活直径约0.5毫米的斑片状区域，覆盖已确定关键特征的电极穿刺部位。由于光学成像中的信号反映了这些区域的平均神经元活动，该结果直接表明了对相似特征做出反应的细胞的区域聚类。
