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[黏液性水肿——激素研究的早期模型]

[Myxedema--an early model for hormone research].

作者信息

Hansen L K

机构信息

Seksjon for medisinsk historie, Det medisinske fakultetsbibliotek, Universitetet i Oslo.

出版信息

Tidsskr Nor Laegeforen. 1996 Mar 30;116(9):1089-91.

PMID:8658478
Abstract

Myxoedema, later known as hypothyroidism, was first described in England in 1873. During the following years it was thought that the disease was caused by a lesion in the nervous system. However, towards the end of the century it was established that the thyroid gland produced an essential substance later known as a hormone. An efficient treatment was introduced, consisting of different forms of tissue extracts. The thyroid gland and myxoedema became a model for the development of the concept of internal secretion. Norwegian physicians were well informed about the scientific advances and quickly accepted the new principles of treatment. This article describes the first Norwegian reference to the disease and its treatment.

摘要

黏液性水肿,后来被称为甲状腺功能减退症,于1873年在英国首次被描述。在接下来的几年里,人们认为这种疾病是由神经系统的病变引起的。然而,到了世纪末,人们确定甲状腺产生一种后来被称为激素的重要物质。一种有效的治疗方法被引入,包括不同形式的组织提取物。甲状腺和黏液性水肿成为内分泌概念发展的一个模型。挪威医生对科学进展了如指掌,并很快接受了新的治疗原则。本文描述了挪威对该疾病及其治疗的首次提及。

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