Ihász M, Bátorfi J, Bálint A, Záborszky A, Regöly-Mérei J, Pósfai G, Barta T, Bereczky M
Third Surgical Department, Semmelweis University Medical School, Budapest, Hungary.
Acta Chir Hung. 1995;35(1-2):63-75.
There is no disease that would have as many and variable complications as Crohn's disease. One of the most common complications is bowel obstruction which can be caused by the angulation of the bowel or by inflammation, or by formation of granulation tissue (32.3%). Very common is the formation of fistulae amongst the bowels involved and other abdominal organs, and also entero-cutaneous fistulae occur frequently (11.3-14.4%). The frequency of complications is increasing with the duration of the illness. If they are life-threatening, only surgical treatment can help. Surgical treatment is also indicated when conservative treatment fails. The most commonly used surgical interventions are bowel resection and, recently, the plasty of stenotic areas. The operative mortality (3.7%) is influenced by the length of the disease and by the numbers of complications. Recurrence is very common in Crohn's disease (30.1-34.9%). The mortality rate of the second operation is 17.5%. The prognosis is usually poor because recurrence can occur years after the primary operation. In Hungary, the frequency of surgically treated patients with Crohn's disease is low, they count for 0.06% of all general surgical operations.
没有哪种疾病会像克罗恩病那样有如此多且多样的并发症。最常见的并发症之一是肠梗阻,它可能由肠管成角、炎症或肉芽组织形成引起(32.3%)。受累肠段与其他腹部器官之间形成瘘管非常常见,肠皮肤瘘也经常出现(11.3 - 14.4%)。并发症的发生率随病程延长而增加。如果并发症危及生命,只有手术治疗才能奏效。当保守治疗失败时也需进行手术治疗。最常用的手术干预措施是肠切除术,近来还有狭窄部位成形术。手术死亡率(3.7%)受病程长短和并发症数量的影响。克罗恩病复发很常见(30.1 - 34.9%)。二次手术的死亡率为17.5%。预后通常较差,因为复发可能在初次手术后数年发生。在匈牙利,接受手术治疗的克罗恩病患者比例较低,占所有普通外科手术的0.06%。