唐氏综合征染色体区域中围绕单 minded 基因聚集的潜在富含 CpG 的岛。（注：“single-minded”可能是特定的专业术语，这里直接保留英文未翻译，因为不清楚其准确的中文释义，可根据实际专业内容进一步修正。） - Suppr

Suppr

超能文献

Potential CpG-rich islands clustering around single-minded gene in Down syndrome chromosomal region.

作者信息

Osoegawa K, Susukida R, Okano S, Kato Y, Lehrach H, Nizetic D, Soeda E

机构信息

RIKEN Gene Bank, Tsukuba Life Science Center, Institute of Physical and Chemical Research (RIKEN), Japan.

出版信息

Mamm Genome. 1996 Jun;7(6):461-3. doi: 10.1007/s003359900134.

DOI:10.1007/s003359900134

PMID:8662217

Abstract

摘要

相似文献

Potential CpG-rich islands clustering around single-minded gene in Down syndrome chromosomal region.

Mamm Genome. 1996 Jun;7(6):461-3. doi: 10.1007/s003359900134.

A 19-kb CpG island associated with single-minded gene 2 in Down syndrome chromosomal region.

DNA Res. 1996 Jun 30;3(3):175-9. doi: 10.1093/dnares/3.3.175.

Single-minded and Down syndrome?

Nat Genet. 1995 May;10(1):9-10. doi: 10.1038/ng0595-9.

Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

Genome Res. 1997 Jun;7(6):615-24. doi: 10.1101/gr.7.6.615.

A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21.

Mol Cell Biol. 1997 Feb;17(2):707-12. doi: 10.1128/MCB.17.2.707.

Recounting a genetic story.

Nature. 2000 May 18;405(6784):283-4. doi: 10.1038/35012790.

A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1).

Genomics. 1997 Sep 1;44(2):237-41. doi: 10.1006/geno.1997.4865.

Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development.

Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9191-5. doi: 10.1073/pnas.92.20.9191.

Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16.

Proc Natl Acad Sci U S A. 1990 May;87(10):3836-40. doi: 10.1073/pnas.87.10.3836.

Mapping of the gene for the p60 subunit of the human chromatin assembly factor (CAF1A) to the Down syndrome region of chromosome 21.

Genomics. 1996 Apr 15;33(2):309-12. doi: 10.1006/geno.1996.0199.

本文引用的文献

3.6-Mb genomic and YAC physical map of the Down syndrome chromosome region on chromosome 21.

Genomics. 1994 Feb;19(3):462-9. doi: 10.1006/geno.1994.1095.

An integrated YAC-overlap and 'cosmid-pocket' map of the human chromosome 21.

Hum Mol Genet. 1994 May;3(5):759-70. doi: 10.1093/hmg/3.5.759.

Molecular mapping of twenty-four features of Down syndrome on chromosome 21.

Eur J Hum Genet. 1993;1(2):114-24. doi: 10.1159/000472398.

The distribution of CpG islands in mammalian chromosomes.

Nat Genet. 1994 Jul;7(3):376-82. doi: 10.1038/ng0794-376.

A high resolution physical map of 2.5 Mbp of the Down syndrome region on chromosome 21.

Hum Mol Genet. 1994 Oct;3(10):1811-7. doi: 10.1093/hmg/3.10.1811.

Cosmid assembly and anchoring to human chromosome 21.

Genomics. 1995 Jan 1;25(1):73-84. doi: 10.1016/0888-7543(95)80111-x.

Single-minded and Down syndrome?

Nat Genet. 1995 May;10(1):9-10. doi: 10.1038/ng0595-9.

Localization of 102 exons to a 2.5 Mb region involved in Down syndrome.

Hum Mol Genet. 1995 Aug;4(8):1305-11. doi: 10.1093/hmg/4.8.1305.

Number of CpG islands and genes in human and mouse.

Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11995-9. doi: 10.1073/pnas.90.24.11995.

CpG islands in vertebrate genomes.

J Mol Biol. 1987 Jul 20;196(2):261-82. doi: 10.1016/0022-2836(87)90689-9.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验