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多学科团队在软组织肉瘤治疗中的重要性。

The importance of a multidisciplinary group in the treatment of soft tissue sarcomas.

作者信息

Wiklund T, Huuhtanen R, Blomqvist C, Tukiainen E, Virolainen M, Virkkunen P, Asko-Seljavaara S, Björkenheim J M, Elomaa I

机构信息

Department of Radiotherapy and Oncology, Helsinki University Hospital, Finland.

出版信息

Eur J Cancer. 1996 Feb;32A(2):269-73. doi: 10.1016/0959-8049(95)00520-x.

Abstract

In 1987, a multidisciplinary soft tissue sarcoma (STS) group was established and a treatment protocol was set up. By 1993, there were 193 patients with a diagnosis of STS of the superficial trunk or extremities. 134 patients were referred with primary (stage M0) tumours and treated with curative or palliative intention. Nine amputations were performed. 94 (70%) patients were treated with wide or compartment surgery (n = 62) or marginal surgery combined with postoperative radiotherapy (n = 32). According to the protocol, these patients had received adequate treatment. 18 patients have recurred locally (13%) (median follow-up: 36 months). 12 were salvaged. 33 had metastases. The estimated 3-year survival, local control and disease-free survival rates are 79, 87 and 69%, respectively. These results compare favourably with previously published results from this hospital and from a nationwide study. The improved results emphasise the importance of a multidisciplinary STS group.

摘要

1987年,一个多学科软组织肉瘤(STS)小组成立,并制定了治疗方案。到1993年,有193例被诊断为躯干或四肢浅表性STS的患者。134例患者因原发性(M0期)肿瘤前来就诊,并接受了根治性或姑息性治疗。实施了9例截肢手术。94例(70%)患者接受了广泛或间室手术(n = 62)或边缘手术联合术后放疗(n = 32)。根据方案,这些患者接受了充分的治疗。18例患者出现局部复发(13%)(中位随访时间:36个月)。12例得到挽救。33例发生转移。估计3年生存率、局部控制率和无病生存率分别为79%、87%和69%。这些结果与该医院此前发表的结果以及一项全国性研究的结果相比更具优势。结果的改善强调了多学科STS小组的重要性。

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