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实验性多发性骨髓瘤小鼠模型中骨病变的随访:一种使用乳腺钼靶专用X线摄影的体内技术描述

Follow-up of bone lesions in an experimental multiple myeloma mouse model: description of an in vivo technique using radiography dedicated for mammography.

作者信息

Vanderkerken K, Goes E, De Raeve H, Radl J, Van Camp B

机构信息

Department of Haematology and Immunology, Free University Brussels, Belgium.

出版信息

Br J Cancer. 1996 Jun;73(12):1463-5. doi: 10.1038/bjc.1996.277.

Abstract

The evolution of bone lesions in transplantable C57BL/KaLwRjj 5T mouse myeloma (MM) has been followed in vivo. Mice were anaesthetised and a radiograph of the pelvis and hind legs was performed by a radiograph dedicated for mammography. This is the first description of an in vivo technique under experimental conditions whereby the development of bone lesions owing to the MM growth was demonstrated.

摘要

对可移植的C57BL/KaLwRjj 5T小鼠骨髓瘤(MM)骨病变的演变进行了体内跟踪研究。将小鼠麻醉后,使用专门用于乳腺摄影的X光机对骨盆和后腿进行X光摄影。这是首次在实验条件下对一种体内技术的描述,该技术证明了由于MM生长导致的骨病变的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af8c/2074558/741015f8623f/brjcancer00040-0014-a.jpg

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