眼睛进化的新视角。
New perspectives on eye evolution.
作者信息
Halder G, Callaerts P, Gehring W J
机构信息
Department of Cell Biology, University of Basel, Switzerland.
出版信息
Curr Opin Genet Dev. 1995 Oct;5(5):602-9. doi: 10.1016/0959-437x(95)80029-8.
The highly complex eyes of vertebrates, insects and molluscs have long been considered to be of independent evolutionary origin. Recently, however, Pax-6, a highly conserved transcription factor, has been identified as a key regulator of eye development in both mammals and flies. Homologues of Pax-6 have also been identified in species from other phyla, including molluscs. The wide variety of eyes in the animal kingdom may, therefore, have evolved from a single ancestral photosensitive origin.
长期以来，脊椎动物、昆虫和软体动物高度复杂的眼睛一直被认为是独立进化而来的。然而，最近一种高度保守的转录因子——无眼基因（Pax-6）已被确定为哺乳动物和果蝇眼睛发育的关键调节因子。在包括软体动物在内的其他门的物种中也发现了无眼基因的同源物。因此，动物界各种各样的眼睛可能都起源于单一的光敏祖先。
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