Minasian S M, Baklavadzhian O G, Adamian Ts I, Saakian S G, Gulian V S
Aviakosm Ekolog Med. 1995;29(6):32-5.
The peculiarities of the effect of vestibular, somatosensory, motor and limbic areas of brain cortex on the activity of neurons of lateral vestibular nucleus (LVN) are studied in the nembutal and chloralose anesthetized rabbits by the extracellular lead method before and after vibration exposure. It is found that the responses of neurons of Deiters's nucleus at all frequency ranges to stimulation of different areas of the cortex were predominantly of inhibitory type, being more pronounced during stimulation of the vestibular and motor areas. The facilitating corticofugal effect was noted in 20-30 % of cells and more pronounced influence was during stimulation of somatosensory and limbic areas of the cortex. During vibration there was a multidirectional effect of cortical areas on the neuronal activity of LVN. The vibration stimulus decreases an inhibitory effect and increases stimulating influence of vestibular cortex on the activity of Deiters's nucleus. The noted effect was more pronounced in neurons with low frequency of initial activity. On stimulation of other areas of the cortex an increase of inhibitory and suppression of facilitating descending effects were noted. The greatest amount of inhibited neurons was recorded during stimulation of motor cortex. The peculiarities and functional significance of the observed effects are discussed.
采用细胞外引导法，在戊巴比妥钠和水合氯醛麻醉的家兔身上，于振动暴露前后，研究了大脑皮质前庭、躯体感觉、运动和边缘区域对外侧前庭核（LVN）神经元活动影响的特点。结果发现，在所有频率范围内，代特氏核神经元对皮质不同区域刺激的反应主要为抑制型，在前庭和运动区域刺激时更为明显。在20% - 30%的细胞中观察到了促进性皮质离心效应，在刺激皮质的躯体感觉和边缘区域时影响更为明显。在振动过程中，皮质区域对LVN神经元活动有多种方向的影响。振动刺激降低了抑制效应，并增加了前庭皮质对代特氏核活动的刺激影响。上述效应在初始活动频率较低的神经元中更为明显。在刺激皮质的其他区域时，观察到抑制作用增强，促进性下行效应受到抑制。在刺激运动皮质时，被抑制神经元的数量最多。文中讨论了所观察到的效应的特点和功能意义。
