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[氮氧化物或肾上腺素中毒时肺脂质谱的变化]

[Changes in the lipid spectrum of the lungs in poisoning by nitrogen oxides or adrenaline].

作者信息

Rakhmanin Iu A, Kropotov A V, Kushnerova N F, Veselkov O V

出版信息

Gig Sanit. 1995 Nov-Dec(6):3-5.

PMID:8666304
Abstract

The content of lipids and fatty acids was measured in lung tissue of intact rats and animals with lung edema caused by nitrogen oxide or adrenaline. Lung edema was found to involve disagreement between the phospholipid and fatty acid spectra and to increase the permeability of membranes. The toxic and adrenaline-induced edemas were found identical as regards the type of changes in the ratio of fractions of neutral lipids, phospholipids, and fatty acid spectrum, that is, these shifts represent a nonspecific reaction of lung tissue to aggression.

摘要

对完整大鼠以及由一氧化氮或肾上腺素导致肺水肿的动物的肺组织中的脂质和脂肪酸含量进行了测定。发现肺水肿涉及磷脂和脂肪酸谱之间的不一致,并增加了膜的通透性。就中性脂质、磷脂和脂肪酸谱各组分比例的变化类型而言,毒性诱导的水肿和肾上腺素诱导的水肿是相同的,也就是说,这些变化代表了肺组织对侵害的非特异性反应。

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