Yamauchi H, Matsui Y, Shiiya N, Murashita T, Sakuma M, Yasuda K
Department of Cardiovascular Surgery, Hokkaido University, Sapporo, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1996 Apr;44(4):534-8.
Dissection of the interventricular septum is an uncommon manifestation, which is rarely associated with infective endocarditis, aneurysm of sinus of Valsalva and thoracic trauma. We report a 34-year-old male case with aorto-left ventricular communication due to infective endocarditis. The patient had chief complaints of dyspnea on exertion and precordial discomfort. Preoperative laboratory data showed normal white blood cell counts, a slightly elevated CRP, and negative blood culture in bacterial examinations. Echocardiogram revealed progressive dissection of the interventricular septum and stenosis of the left ventricular outflow tract. Disturbance of conduction including progressive atrioventricular block and bundle branch block were found in the electrocardiogram. The dissection extended over 2 x 2 x 2.5 cm in diameter, with an entry located at the basis of the right coronary cusp and reentry communicated to the left ventricle. Operative procedures included the aortic valve replacement with prosthetic valve due to severe inflammation, in addition to resection of the dissecting cavity. Pathological examination of the resected tissue accorded with infective endocarditis in active phase, showing necrosis, small cell infiltration and microabscess. However, a bacterial colony was not found in the surgical specimen. Postoperative course was uneventful and the patient was discharged in satisfactory conditions.
室间隔夹层是一种罕见的表现,很少与感染性心内膜炎、瓦氏窦瘤和胸部创伤相关。我们报告一例34岁男性因感染性心内膜炎导致主动脉-左心室连通的病例。患者主要症状为劳力性呼吸困难和心前区不适。术前实验室数据显示白细胞计数正常、CRP略有升高,细菌学检查血培养阴性。超声心动图显示室间隔进行性夹层和左心室流出道狭窄。心电图发现传导障碍,包括进行性房室传导阻滞和束支传导阻滞。夹层直径超过2×2×2.5 cm,入口位于右冠状动脉瓣叶基部,再入口与左心室相通。手术操作包括因严重炎症行人工瓣膜主动脉瓣置换术,此外还切除夹层腔。切除组织的病理检查符合活动期感染性心内膜炎,表现为坏死、小细胞浸润和微脓肿。然而,手术标本中未发现细菌菌落。术后病程顺利,患者出院时情况良好。