Johnson D E
Recent Results Cancer Res. 1977(60):221-30. doi: 10.1007/978-3-642-81095-4_24.
The use of retroperitoneal lymphadenectomy in the management of 152 patients with nonseminomatous germ cell tumors of the testis treated at Anderson Hospital has been reviewed. Complications consisting of wound infection (six cases), acute pancreatitis (two cases), lymphocyst formation (two cases), and chylous ascites (one case) developed in 6.4% of patients. Although ejaculatory impotence is common postoperatively, only 12 marriage units were desirous of having children and 7 of these have had uncomplicated and successful pregnancies. No instances of erectile impotence developed in this series. The indications for the procedure have been defined with regard to accurate staging, combined therapy, and, in selected instances of advanced disease, as a means of monitoring the effects of chemotherapy. The importance of this operative procedure in the multimodal management of patients with nonseminomatous germ cell tumors of the testis cannot be overemphasized.
回顾了安德森医院对152例睾丸非精原细胞性生殖细胞瘤患者采用腹膜后淋巴结清扫术的治疗情况。6.4%的患者出现了并发症,包括伤口感染(6例)、急性胰腺炎(2例)、淋巴囊肿形成(2例)和乳糜性腹水(1例)。虽然射精功能障碍在术后很常见,但只有12对夫妇希望生育,其中7对妊娠过程顺利且成功。本系列中未出现勃起功能障碍的病例。该手术的适应证已根据准确分期、联合治疗以及在某些晚期疾病的特定情况下作为监测化疗效果的手段进行了明确。在睾丸非精原细胞性生殖细胞瘤患者的多模式治疗中,这种手术的重要性再怎么强调也不为过。