Barroso-Vicens E, Ramirez G, Rabb H
Division of Nephrology and Hypertension, Department of Internal Medicine, James A. Haley Veterans Hospital, Tampa, Florida, USA.
Transplantation. 1996 Jun 15;61(11):1655-6. doi: 10.1097/00007890-199606150-00020.
Organ transplantation and the use of immunosuppressive therapy has been associated with an increased incidence of malignancy. We report the case of a long-term renal transplant recipient who developed concomitant skin cancers, non-Hodgkin's lymphoma, and malignant fibrous histiocytoma. The development of three seemingly unrelated cancers in the same patient illustrates the favorable host environment in transplant patients for the development of malignancies.
器官移植及免疫抑制疗法的使用与恶性肿瘤发病率的增加有关。我们报告了一例长期肾移植受者的病例,该患者同时发生了皮肤癌、非霍奇金淋巴瘤和恶性纤维组织细胞瘤。同一患者出现三种看似不相关的癌症,这说明了移植患者体内有利于恶性肿瘤发生的宿主环境。