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乳膏的流变学研究。II. 含水量对流变学特性的影响。

Rheological studies of creams. II. Effect of water content on rheological characteristics.

作者信息

Taleb A, Erös I

机构信息

Department of Pharmaceutical Technology of Albert Szent-György Medical University.

出版信息

Acta Pharm Hung. 1996 Mar;66(2):71-6.

PMID:8669280
Abstract

25 creams with different water content was prepared by means of five self-emulsifying waxes. The variables were the ratio of the structure forming components of the lipophilic phase, the hydrophilic emulsifier and the water content. It was concluded from the flow curves, that the investigated creams were thixotropic systems independently of the water content. The yield value, the initial, the equilibrium and the plastic viscosity decreased exponentially with the concentration of the emulsified water. The slope of the linearized exponential curve is an important structural parameter. The measure of the this parameter provides information about the position of water in the gel structure.

摘要

通过五种自乳化蜡制备了25种不同含水量的乳膏。变量为亲脂相结构形成成分、亲水性乳化剂和含水量的比例。从流动曲线得出的结论是,所研究的乳膏是触变体系,与含水量无关。屈服值、初始粘度、平衡粘度和塑性粘度随乳化水浓度呈指数下降。线性化指数曲线的斜率是一个重要的结构参数。该参数的测量提供了关于水在凝胶结构中位置的信息。

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