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[Studies of the radiation-protective effects of indralin on the hematopoietic system of different species of animals].

作者信息

Vasin M V, Antipov V V, Chernov G A, L'vova T S, Koroleva L V, Semenova L A, Liutykh V P, Komarova S N, Gaĭdamakin N A, Vilkina G A

出版信息

Radiats Biol Radioecol. 1996 Mar-Apr;36(2):168-89.

PMID:8673216
Abstract

The experiments were made on mice, guinea pigs and dogs. Radioprotector indraline increased radioresistant state of hematopoietic stem cells in vivo and in vitro, decreased the amount of post-radiation chromosome aberrations in marrow, induced more early and intensive post-radiation proliferative repair of marrow and spleen, faster regeneration of the initial amount of leukocytes, thrombocytes and erythrocytes in blood of mice, guinea pigs and dogs. Antiradiation efficiency of indraline in hematopoietic system is equal to 1.5-2 by FMD. Radioprotective mechanism of indraline effect on hematopoietic system is discussed.

摘要

相似文献

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Radiats Biol Radioecol. 1996 Mar-Apr;36(2):168-89.
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