[含硫天然气急性中毒所致肺部疾病的临床体征及发病机制的若干方面]
[Several aspects of clinical signs and pathogenesis of pneumopathies in acute poisoning caused by sulfur-containing natural gas].
作者信息
Trubnikov G A, Orlov M A, Val'ter V E, Bochanovskiĭ V A, Davydova L D, Rezaev A A, Pushkarev V A, Velikanov E B, Trizno N N
出版信息
Med Tr Prom Ekol. 1996(1):6-12.
The article summarizes and analyzes data on 32 cases of acute intoxication varying in severity and caused by inhalation of sulfur-containing natural gas of Astrakhan gas deposit (SCNGAGD). The data were obtained in experimental poisoning of 120 Wistar rats with the gas. Pneumopathies (toxic pulmonary edema, pneumonitis, asthmatic bronchitis, alveolitis) appeared to play the central role among other syndromes of the intoxication by SCNGAGD. Mechanisms of the pneumopathies were traced to morphologic disorders of blood-lung barrier, compromised functions of lung surfactant, disturbances in lipid peroxidation and anaerobic glycolysis.
本文总结并分析了32例因吸入阿斯特拉罕气田含硫天然气（SCNGAGD）导致的不同严重程度急性中毒病例的数据。这些数据是在120只Wistar大鼠吸入该气体进行实验性中毒时获得的。在SCNGAGD中毒的其他综合征中，肺部疾病（中毒性肺水肿、肺炎、哮喘性支气管炎、肺泡炎）似乎起着核心作用。肺部疾病的机制可追溯到血 - 肺屏障的形态学紊乱、肺表面活性物质功能受损、脂质过氧化和无氧糖酵解的紊乱。
Zotero 插件